Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
- Creator: Keaton, Jacob M. , Kamali, Zoha , Young, William J. , Lehtimäki, T , Raitakari, OT , Johnson, AD , Newton-Cheh, C , Brown, MJ , Dominiczak, AF , Sever, PJ , Poulter, N , Chambers, JC , Elosua, R , Traylor, Matthew , Siscovick, D , Esko, T , Metspalu, A , Strawbridge, RJ , Laakso, M , Hamsten, A , Hottenga, J-J , de Geus, E , Morris, AD , Palmer, CNA , Giri, Ayush , Nolte, IM , Milaneschi, Y , Marten, J , Wright, A , Zeggini, E , Howson, JMM , O'Donnell, CJ , Spector, T , Nalls, MA , Simonsick, EM , Zheng, Zhili , Liu, Y , van Duijn, CM , Butterworth, AS , Danesh, JN , Menni, C , Wareham, NJ , Khaw, K-T , Sun, YV , Wilson, PWF , Cho, K , Zeng, Jian , Visscher, PM , Denny, JC , Million Veteran Program, , Lifelines Cohort Study, , CHARGE consortium, , ICBP Consortium, , Levy, D , Edwards, TL , Munroe, PB , Snieder, H , Chasman, Daniel I. , Warren, HR , Morris, Andrew P. , Caulfield, Mark J. , Hwang, Shih-Jen , Kooner, Jaspal S. , Xie, Tian , Attia, John R. , Attia, JR , Morrison, AC , Loos, RJF , Kristiansson, K , Schmidt, R , Hicks, AA , Pramstaller, PP , Nelson, CP , Samani, NJ , Vaez, Ahmad , Risch, L , Gyllensten, U , Melander, O , Riese, H , Wilson, JF , Campbell, H , Rich, SS , Psaty, BM , Lu, Y , Rotter, JI , Williams, Ariel , Guo, X , Rice, KM , Vollenweider, P , Sundström, J , Langenberg, C , Tobin, MD , Giedraitis, V , Luan, J , Tuomilehto, J , Kutalik, Z , Goleva, Slavina B. , Ripatti, S , Salomaa, V , Girotto, G , Trompet, S , Jukema, JW , van der Harst, P , Ridker, PM , Giulianini, F , Vitart, V , Goel, A , Ani, Alireza , Watkins, H , Harris, SE , Deary, IJ , van der Most, PJ , Oldehinkel, AJ , Keavney, BD , Hayward, C , Campbell, A , Boehnke, M , Scott, LJ , Evangelou, Evangelos , Boutin, T , Mamasoula, C , Järvelin, M-R , Peters, A , Gieger, C , Lakatta, EG , Cucca, F , Hui, J , Knekt, P , Enroth, S , Hellwege, Jacklyn N. , De Borst, MH , Polašek, O , Concas, MP , Catamo, E , Cocca, M , Li-Gao, R , Hofer, E , Schmidt, H , Spedicati, B , Waldenberger, M , Yengo, Loic , Strachan, DP , Laan, M , Teumer, A , Dörr, M , Gudnason, V , Cook, JP , Ruggiero, D , Kolcic, I , Boerwinkle, E , Traglia, M
- Resource Type: journal article
- Date: 2024
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
- Creator: Shrine, Nick , Izquierdo, Abril G. , Hobbs, Brian D. , Foong, RE , Harris, SE , Taylor, A , Redmond, P , Cook, JP , Mahajan, A , Lind, L , Palviainen, T , Lehtimäki, T , Raitakari, OT , Moll, Matthew , Kaprio, J , Rantanen, T , Pietiläinen, KH , Cox, SR , Pennell, CE , Hall, GL , Gauderman, WJ , Brightling, C , Wilson, JF , Vasankari, T , Kim, Wonji , Laitinen, T , Salomaa, V , Mook-Kanamori, DO , Timpson, NJ , Zeggini, E , Dupuis, J , Hayward, C , Brumpton, B , Langenberg, C , Weiss, S , Tal-Singer, Ruth , Homuth, G , Schmidt, CO , Probst-Hensch, N , Jarvelin, M-R , Morrison, AC , Polasek, O , Rudan, I , Lee, J-H , Sayers, I , Rawlins, EL , Bakke, Per , Dudbridge, F , Silverman, EK , Strachan, DP , Walters, RG , Morris, AP , London, SJ , Cho, MH , Wain, LV , Hall, IP , Tobin, MD , Fawcett, Katherine A. , John, Catherine , Coley, Kayesha , Piga, Noemi Nicole , Pozarickij, Alfred , Chen, Jing , Wang, Carol A. , Pennell, Craig E. , Chen, Z , Li, L , China Kadoorie Biobank Collaborative Group, , Wijnant, SRA , Lahousse, L , Brusselle, G , Uitterlinden, AG , Manichaikul, A , Packer, Richard , Oelsner, EC , Rich, SS , Barr, RG , Kerr, SM , Vitart, V , Brown, MR , Wielscher, M , Imboden, M , Jeong, A , Bartz, TM , Hall, Robert J. , Gharib, SA , Flexeder, C , Karrasch, S , Gieger, C , Peters, A , Stubbe, B , Hu, X , Ortega, VE , Meyers, DA , Bleecker, ER , Guyatt, Anna L. , Gabriel, SB , Gupta, N , Smith, AV , Luan, J , Zhao, J-H , Hansen, AF , Langhammer, A , Willer, C , Bhatta, L , Porteous, D , Batini, Chiara , Smith, BH , Campbell, A , Sofer, T , Lee, J , Daviglus, ML , Yu, B , Lim, E , Xu, H , O'Connor, GT , Thareja, G , Thompson, Rebecca J. , Albagha, OME , Qatar Genome Program Research (QGPR) Consortium, , Suhre, K , Granell, R , Faquih, TO , Hiemstra, PS , Slats, AM , Mullin, BH , Hui, J , James, A , Pavuluri, Chandan , Beilby, J , Patasova, K , Hysi, P , Koskela, JT , Wyss, AB , Jin, J , Sikdar, S , Lee, M , May-Wilson, S , Pirastu, N , Malik, Vidhi , Kentistou, KA , Joshi, PK , Timmers, PRHJ , Williams, AT , Free, RC , Wang, X , Morrison, JL , Gilliland, FD , Wang, CA
- Resource Type: journal article
- Date: 2023
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
- Creator: Justice, Anne E. , Karaderi, Tugce , Highland, Heather M. , Young, Kristin L. , Graff, Mariaelisa , Lu, Yingchang , Turcot, Valérie , Auer, Paul L. , Fine, Rebeccaa S. , Guo, Xiuqing , Schurmann, Claudia , Lempradl, Adelheid , Marouli, Eirini , Mahajan, Anubha , Winkler, Thomas W. , Locke, Adam E. , Medina-Gomez, Carolina , Esko, Tõnu , Vedantam, Sailaja , Giri, Ayush , Pennell, Craig E. , Wang, Carol A. , Lo, Ken Sin , Alfred, T , Mudgal, P , Ng, MCY , Heard-Costa, NL , Feitosa, MF , Manning, AK , Willems, SM , Sivapalaratnam, S , Abecasis, G , Alam, DS , Allison, M , Amouyel, P , Arzumanyan, Z , Balkau, B , Bastarache, L , Bergmann, S , Bielak, LF , Blüher, M , Boehnke, M , Boeing, H , Boerwinkle, E , Böger, CA , Bork-Jensen, J , Bottinger, EP , Bowden, DW , Brandslund, I , Broer, L , Burt, AA , Butterworth, AS , Caulfield, MJ , Cesana, G , Chambers, JC , Chasman, DI , Chen, YDI , Chowdhury, R , Christensen, C , Chu, AY , Collins, FS , Cook, JP , Cox, AJ , Crosslin, DS , Danesh, J , de Bakker, PIW , Denus, SD , Mutsert, RD , Dedoussis, G , Demerath, EW , Dennis, JG , Denny, JC , Angelantonio, ED , Dörr, M , Drenos, F , Dubé, MP , Dunning, AM , Easton, DF , Elliott, P , Evangelou, E , Farmaki, AE , Feng, S , Ferrannini, E , Ferrieres, J , Florez, JC , Fornage, M , Fox, CS , Franks, PW , Friedrich, N , Gan, W , Gandin, I , Gasparini, P , Giedraitis, V , Girotto, G , Gorski, M , Grallert, H , Grarup, N , Grove, ML , Gustafsson, S , Haessler, J , Hansen, T , Hattersley, AT
- Resource Type: journal article
- Date: 2019
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- Creator: Giri, Ayush , Hellwege, Jacklyn N. , Keaton, Jacob M. , Park, Jihwan , Qiu, Chengxiang , Warren, Helen R. , Torstenson, Eric S. , Kovesdy, Csaba P. , Sun, Yan V. , Wilson, Otis D. , Robinson-Cohen, Cassianne , Roumie, Christianne L. , Chung, Cecilia P. , Birdwell, Kelly A. , Damrauer, Scott M. , DuVall, Scott L. , Klarin, Derek , Cho, Kelly , Wang, Yu , Evangelou, Evangelos , Attia, John , Oldmeadow, Christopher , Wei, WQ , Jarvelin, MR , Hennig, BJ , Timpson, NJ , Smith, JC , Xu, Y , Matheny, ME , Siew, EE , Lindgren, C , Herzig, KH , Dedoussis, G , Denny, JC , Psaty, BM , Howson, JMM , Munroe, PB , Newton-Cheh, C , Caulfield, MJ , Elliott, P , Gaziano, JM , Concato, J , Wilson, PWF , Tsao, PS , Velez Edwards, DR , Susztak, K , O¿Donnell, CJ , Hung, AM , Edwards, TL , Cabrera, Claudia P. , Wain, LV , Shrestha, R , Mautz, BS , Akwo, EA , Sargurupremraj, M , Debette, S , Boehnke, M , Scott, LJ , Luan, J , Zhao, JH , Willems, SM , Thériault, S , Shah, N , Almgren, P , Li-Gao, R , Verweij, N , Boutin, TS , Mangino, M , Ntalla, I , Feofanova, E , Surendran, P , Cook, JP , Karthikeyan, S , Lahrouchi, N , Liu, C , Sepúlveda, N , Richardson, TG , Kraja, A , Amouyel, P , Farrall, M , Poulter, NR , Laakso, M , Zeggini, E , Sever, P , Scott, RA , Langenberg, C , Wareham, NJ , Conen, D , Palmer, CNA , Chasman, DI , Ridker, PM , Melander, O , Mook-Kanamori, DO , van der Harst, P , Cucca, F , Schlessinger, D , Hayward, C , Spector, TD
- Resource Type: journal article
- Date: 2019